Researcher Dr. Hazem Elewa
Recent work focused on reviewing the role of genetic and non-genetic factors on warfarin dosing in the MENA region and in Qatari patients. Bader LA, Elewa H. [The Impact of Genetic and Non-Genetic Factors on Warfarin Dose Prediction in MENA Region: A Systematic Review. PloS one 11.12 (2016): e0168732.].
Research Symposium
The 3rd Annual Health Cluster Research Symposium was held on Saturday April 21st at the Qatar University Research Complex. The event was a huge success with a great turnout of around 100 participants from QU Health Colleges: College of Medicine, College of Health Sciences and College of Pharmacy, and the Biomedical Research Center. Several faculty members and students (both undergraduate and postgraduate) participated in the podium presentations and poster sessions.
Congratulations to the Winners at the QU Health 3rd Annual Research Symposium 2018
- Dr. Abdelali Agouni- 1st Place Oral Presentation- Faculty level (Title: Anti-neoplastic effects of metformin against renal clear cell carcinoma)
- Dr. Hesham M. Korashy - 2nd Place Oral Presentation- Faculty level (Title: Molecular mechanisms of gefitinib‐induced cardiovascular toxicity in rats: the role of PTEN‐AKT‐FoxO3a signaling pathway)
- Ola Hussein- 1st Place Poster Presentation- Undergraduate level
- Huda Barhoosh- 2nd place Poster Presentation- Undergraduate level
- Sara Abdulrhim and Rana Saleh- 1st Place Poster Presentation- Postgraduate level
- Alaa Mahmoud- 2nd Place Poster Presentation- Postgraduate level
Researcher Dr. Abdelali Agouni
Recent work led by Dr. Abdelali Agouni demonstrated for the first time the beneficial effects of pharmacological induction of Heme Oxygenase (HO)-1 in preventing high glucose-mediated activation of endoplasmic reticulum stress response in cultured endothelial cells leading to an improvement in endothelial dysfunction, the initial step in the development of atherosclerosis, characterized by a protection against endothelial cell death and improved angiogenic capacity. This work further highlighted the therapeutic potential of HO-1 induction in the treatment of cardiovascular complications of diabetes.
[Maamoun H, Zachariah 1, McVey JH, Green FR, Agouni A. Heme oxygenase (HO)-1 induction prevents Endoplasmic Reticulum stress-mediated endothelial cell death and impaired angiogenic capacity. Biochemical Pharmacology, 2017;127:46-59. doi: 10.1016/j.bcp.2016.12.009]